Australia

• Three Sisters (Australia), a rock formation near Katoomba, NSW
• The Three Sisters (Queensland), three islands
• Three Sisters Island (Tasmania), three small islands

Canada

• The Three Sisters (Alberta), three peaks in the Canadian Rockies near Canmore, Alberta
• The Three Sisters (Lake Huron), three islands in Lake Huron
• The Three Sisters (Temagami), three lakes in Temagami, Ontario
• Three Sisters (Elk Valley), three peaks in the Canadian Rockies just north of the town of Fernie, British Columbia
• Three Sisters Range, three peaks in the Stikine Country, British Columbia
• Three Sisters Lakes Provincial Park, a park near Hixon, British Columbia
• Three Sisters, a rock formation along the shore of Cape Chignecto Provincial Park

Ireland

• The Three Sisters (Ireland), three rivers
• An Triúr Deirfiúr (Irish for The Three Sisters), three peaks

South Africa

• Three Sisters (Northern Cape), a rock formation consisting of a group of three conical peaks situated on the watershed between Beaufort West and Richmond

United Kingdom

• Three Sisters (Glen Coe), three ridges
• Three Sisters Recreation Area, Wigan

United States

• Three Sisters (Los Angeles County), a mountain range in California
• Three Sisters (Riverside County), a mountain range in California
• Three Sisters (Siskiyou County), a mountain range in California
• Three Sisters (District of Columbia), three islands
• Three Sisters Springs (Florida)
• Three Sisters (Georgia), three peaks
• Three Sisters (Oregon), three volcanoes
• Three Sisters Wilderness, Oregon
• Three Sisters (Pittsburgh), three bridges in Pennsylvania

• Three Sisters (play), a play by Anton Chekhov
  • The Three Sisters (1966 film), an American film
  • Three Sisters (1970 Olivier film), a British film
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