A meteor shower destroys the cities, Rome and the Vatican city. Pope and the six cardinals manage to escape carnage. They are later found to be the archangels, who have been handed the responsibility to save the city.
Two french police arrest a criminal Paul, who attacks the cops. He later has a cardiac arrest and dies. But, when the policemen are on the way to hospital, he gets well, as if nothing happened.
The patients start becoming murderers, who kill every face who strikes them. The patients, doctors and nurses are zombified. David's collegue gets zombified too and she tries to murder David. But David manages to escape the odds. He finds an archangel Victoria, who gives him a temporary treatment.
The group of archangels try to get control over the situation and kill the zombies, but Paul's team is attacking them recklessly. Later, it is discovered that Paul was one in the four horsemen of The Book of Revelations. He is trying the unleash on the world, the army of Satan.
The archangels take rebirth to kill the man, Paul and his army and save the place.