When stuntman Sambandham (Kamal Haasan) and Dr. Janaki (Simran) come across each other at his brother Anand's (Abbas) and her best friend Malathi's (Sneha) hastily planned wedding ceremony, they instantly develop a dislike for each other. They both have a very low opinion of the opposite sex, and staunchly believe marriage is not the way to go for the two newly-weds, whom they try to discourage from proceeding further.

Janaki convinces Malathi to test out her theory that men are after only one thing, by forcing Malathi to delay their consummation for three months. She is sure Anand will not be able to do so and this will prove to Malathi that Anand is just another low-class male, like all others. Sambandham, upon hearing about this new development, lures Malathi to find Anand with a "girlfriend", hoping she would change her attitude and be a more dutiful wife. The plan backfires and Malathi and Anand end up in divorce.

Later, Janaki is given a watch by her aunt to wear as a good luck charm. Sambandham gets seriously hurt during a stunt shoot and Janaki herself performs the surgery on him. After the surgery, while looking at the X-rays, she is horrified to discover that the watch on her wrist has accidentally ended up in Sambandham's stomach. Janaki tries various ways of getting the watch out. By this time, Sambandham begins to fall in love with Janaki and gets engaged to her. After the engagement, Janaki is successful in removing the watch from Sambandham's stomach. Following the surgery, Janaki calls off the engagement and Sambandham leaves with a heavy heart.

Several days later, he accepts an arranged marriage proposal from a female weightlifter in an attempt to forget about Janaki. Upon realizing her intrusive behaviour, Janaki helps Anand and Malathi reconcile and decides to confess her love for Sambandham at their wedding ceremony. On the other hand, the weightlifter is not interested to marry Sambandham and wants to elope with her boyfriend. Sambandham helps them elope .The weightlifter's father (Manivannan) and Sambandham's uncle (Santhana Bharathi) chase the trio to a police station where the weightlifter and her boyfriend marry. Janaki too arrives at the police station and finally confesses her love for Sambandham.

Kamal Haasan initially approached Moulee to make a film for his own production house, but efforts were unfruitful. Subsequently, the film was started under P. L. Thenappan in August 2001 and the shoot was complete within three months. The film's invitation card for the launch was shaped in the form of the alphabet "K", which formed a significant theme throughout the film. The card also featured images of Devayani who was later replaced in the film by Sneha. Devayani was removed after she went on honeymoon following her sudden marriage and thus she was unable to fulfil her original schedules. Kamal Haasan's character was a stunt double under Vikram Dharma in the film and the stunt director had used the air-ramp for the first time in a Tamil film.

The film was initially slated to be released coinciding with the Diwali season of 2001, but due to the delay of Kamal Haasan's other film, Aalavandhan, it was shifted to January 2002. During the making of the film, the significance of the initial "K" was hidden before Kamal Haasan revealed at a press conference two weeks before release that it stood for "Kalyanam" (Marriage), which the lead characters despised of.

Soundtrack is composed by Deva and lyrics for all songs were written by Vaali, Kabilan and Pa. Vijay.

• Gadothkaja — Srinivas, Mahalakshmi Iyer
• Kandhasamy Maadasamy — Kamal Haasan
• Sakalakala Vallavane - Hariharan, Sujatha
• Endi Sudamani — Anuradha Sriram
• Penne Kadhal — KK
• Dindukallu — Shankar Mahadevan, Mahalakshmi Iyer

The satellite rights of the film were secured by Sun TV. The film was given a "U" certificate by the Indian Censor Board.

The film was initially slated to be released coinciding with the Diwali season of 2001, but due to the delay of Kamal Haasan's other film, Aalavandhan, it was shifted to January 2002.^[11] Pammal K. Sambandam took a big opening at the box office,^[12] running 100 days in 80 centers.^[13][14]

The film received above average reviews with The Hindu claiming that "if Mouli had sustained the humorous strain throughout, PKS would have turned out to be a complete comic treat from start to finish. Why he did not do it remains a riddle." The critic also praised the lead performances and Crazy Mohan's dialogue writing.^[15] Rediff.com described it as "an average film", stating that the only "real highpoint is 'Crazy' Mohan's dialogues".^[16]

Upon release, the film was also dubbed into the Telugu language as Brahmachari. It was later remade in Hindi as Kambakkht Ishq in 2009 by Sajid Nadiadwala with Akshay Kumar and Kareena Kapoor in the lead roles.^[17][18]