Parosi tells the story of two sisters, Jahan Ara (Khalida Riyasat) who is a single parent as her husband Jamal Shah left her for a wealthier woman, and Roshan Ara (Marina Khan), who is much more mature and composed as compared to her elder sister. They, along with Haryali Bua (Badar Khalil), come to live in a house they have rented from Ali Ejaz who is a very strict man living with his nephew Arsal (Saleem Sheikh). The comedy of errors starts as Jahan makes the life of her landlord miserable. Roshan Ara and Arsal fall in love.

• Ali Ejaz as Shahnawaz Ali Khan, aka Agha Jani, the landlord; uncle of Arsal
• Khalida Riyasat as Jehan Ara, the middle sister; has a son, Ali, with ex-husband Malik Iqbal
• Marina Khan as Roshan Ara aka Munni, youngest of three sisters; she makes documentary films
• Badar Khalil as Haryali Begum; maidservant in the sisters' household.
• Saleem Sheikh as Arsal, nephew (sister's son) of Aga Jani.
• Jamal Shah as Malik Iqbal, Jehan Ara's husband
• Shamim Hilaly as Bari Aapa (Mrs. Asif), elder sister of Roshan Ara and Jehan Ara
• Humera Syed as Nani, maternal grandmother of the sisters
• Parveen Rasheed as Amma, mother of the sisters
• Sikander as Ali, Jehan Ara and Malik Iqbal's son

The drama serial was shot in Murree and Islamabad and was well received by the audiences. It is considered to be one of Haseena Moin's best works. It featured the great actresses Khalida Riyasat and Marina Khan and it was a treat for the viewers to watch both of them perform together. The drama serial has had several reruns on TV and its DVDs are still in demand.

Padosi's soundtrack featured two songs. One was a ghazal called Abhi Kuch Din Lagen Ge sung by Mehnaz with poetry by Iftikhar Arif. The second song was called Ga Raha Tha Koi sung by Ali Haider with poetry by Nasir Kazmi. Both were composed by Arshad Mahmood, and are frequently used during the show.

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