Well-known invasions of the area have been predominantly through the Khyber Pass, such as the invasions by Darius I, Genghis Khan and later Mongols such as Duwa, Qutlugh Khwaja and Kebek. Prior to the Kushan era, the Khyber Pass was not a widely used trade route. Among the Muslim invasions of the Indian subcontinent, the famous invaders coming through the Khyber Pass are Mahmud Ghaznavi, and the Afghan Muhammad Ghori and the Turkic-Mongols.

Finally, Sikhs under Ranjit Singh captured the Khyber Pass in 1834 until they were defeated by the forces of Wazir Akbar Khan in 1837. Hari Singh Nalwa, who manned the Khyber Pass for years, became a household name in Afghanistan.

To the north of the Khyber Pass lies the country of the Mullagori tribe. To the south is Afridi Tirah, while the inhabitants of villages in the Pass itself are Afridi clansmen. Throughout the centuries the Pashtun clans, particularly the Afridis and the Afghan Shinwaris, have regarded the Pass as their own preserve and have levied a toll on travellers for safe conduct. Since this has long been their main source of income, resistance to challenges to the Shinwaris' authority has often been fierce.

For strategic reasons, after the First World War the British built a heavily engineered railway through the Pass. The Khyber Pass Railway from Jamrud, near Peshawar, to the Afghan border near Landi Kotal was opened in 1925.

During World War II concrete "dragon's teeth" (tank obstacles) were erected on the valley floor due to British fears of a German tank invasion of British India.

The Pass became widely known to thousands of Westerners and Japanese who traveled it in the days of the hippie trail, taking a bus or car from Kabul to the Afghan border. At the Pakistani frontier post, travelers were advised not to wander away from the road, as the location was a barely controlled Federally Administered Tribal Area. Then, after customs formalities, a quick daylight drive through the Pass was made. Monuments left by British Army units, as well as hillside forts, could be viewed from the highway.

The area of the Khyber Pass has been connected with a counterfeit arms industry, making various types of weapons known to gun collectors as Khyber Pass copies, using local steel and blacksmiths' forges.

Current conflicts

During the war in Afghanistan, the Khyber Pass has been a major route for resupplying military armament and food to the NATO forces in the Afghan theater of conflict since the US started the invasion of Afghanistan in 2001. Almost 80 percent of the NATO and US supplies that are brought in by road were transported through the Khyber Pass. Furthermore, it has also been used to transport civilians from the Afghan side to the Pakistani one. Until the end of 2007, this route had been relatively safe since the tribes living there (mainly Afridi, a Pashtun tribe) were paid by the Pakistani government to keep the area safe. However, since that year, the Taliban began to control the region, and so there started to exist wider tensions in their political relationship.

Since the end of 2008, supply convoys and depots in this western part have increasingly come under attack by elements from or supposedly sympathetic to the Pakistani Taliban.

In January 2009, Pakistan sealed off the bridge as part of a military offensive against Taliban guerrillas. This military operation was mainly focused on Jamrud, a district on the Khyber road. The target was to “dynamite or bulldoze homes belonging to men suspected of harboring or supporting Taliban militants or carrying out other illegal activities”. The result meant that more than 70 people were arrested and 45 homes were destroyed. In addition, two children and one woman were killed. As a response, in early February 2009, Taliban insurgents cut off the Khyber Pass temporarily by blowing up a key bridge.

This increasingly unstable situation in northwest Pakistan, made the US and NATO broaden supply routes, through Central Asia (Turkmenistan, Uzbekistan and Tajikistan). Even the option of supplying material through the Iranian far southeastern port of Chabahar was considered.

In 2010, the already complicated relationship with Pakistan (always accused by the US of hosting the Taliban in this border area without reporting it) became tougher after the NATO forces, under the pretext of mitigating the Taliban's power over this area, executed an attack with drones over the Durand line, passing the frontier of Afghanistan and killing three Pakistani soldiers. Pakistan answered by closing the pass on 30 September which caused a convoy of several NATO trucks to queue at the closed border. This convoy was attacked by extremists apparently linked to Al Qaida which caused the destruction of more than 29 oil tankers and trucks and the killing of several soldiers.^[8] NATO chief members had to issue a formal apology to the Pakistan government so the supply traffic at this pass could be restored.

In August 2011, the activity at the Khyber pass was again halted^[9] by the Khyber Agency administration due to the more possible attacks of the insurgency over the NATO forces, which had suffered a period of large number of assaults over the trucks heading to supply the NATO and ISAF coalitions all over the frontier line. This instability made the Pakistan Oil Tanker Owners Association demand more protection from the Pakistani and US government threatening not to supply fuel for the Afghan side.

A number of locations, around the world, have been named after the Khyber Pass:

• A suburb of Civil Lines, Delhi, India, is named after this pass.^[10][11][12]
• 'Khyber Pass' is Cockney rhyming slang meaning 'arse'. This use is alluded to in the 1968 film Carry On Up the Khyber.
• Khyber Pass Road is a major road in the suburb of Newmarket, Auckland, New Zealand.
• An artificial rockwork feature at East Park, Kingston upon Hull, UK.^[13][14]
• A steep and twisting road up the West Cliff at Whitby, UK.
• Khyber Pass Pub in Philadelphia, Pennsylvania.
• The podcast Twilight Histories has an episode called "Napoleon in Afghanistan" which partly takes place in the Khyber Pass.
• The Vampire Weekend song "M79" references the Khyber Pass.
• The Tom Cochrane song "Life Is a Highway" (covered by Rascal Flatts and others) references the Khyber Pass.
• The album Rio Grande Blood by Ministry (2006) has a song called "Khyber Pass" which references it as a possible hiding place for then missing and at large Osama bin Laden. This song was also featured at the end of the film The Hurt Locker.
• Referenced in the song "Red War" by Probot, featuring Max Cavalera on vocals.
• A spa hotel in Gulmarg Jammu and Kashmir is named Khyber Himalayan Resort and Spa.
• British rock band Pink Floyd references the Khyber in their song "Up the Khyber", featured on the soundtrack to the film More
• 'Khyber Pass' is a mountain bike trail connecting the Top of the World trail at Whistler Resort to the Whistler Creekside Village.

• Bab-e-Khyber
• Ali Masjid
• Battle of Ali Masjid
• Carry On... Up the Khyber, film
• Dasht-e Yahudi
• Durand Line
• Federally Admin