• Black box (phreaking), a device to defeat telephone toll charges
• Eucalyptus largiflorens, a tree species with the common name black box

Transportation

• Event data recorder, a device installed in some automobiles to record information related to vehicle crashes or accidents
• Flight recorder, an aircraft-borne device used in disaster investigation, consisting of a flight data recorder and cockpit voice recorder
  • Flight operations quality assurance
  • Quick access recorder
• Train event recorder, a device that records data about the operation of train controls and performance
• Voyage data recorder, a device designed to collect data from various sensors on board a ship

Computing

• Black box theory, a systems engineering theory for black boxes
• Black-box testing, a form of software testing that involves adjusting inputs to an application without reference to the source code of the application
• Blackbox, a window manager that works on X Window System platforms
• BlackBox Component Builder, software development environment for Component Pascal
• Sun Modular Datacenter, prototype name Project Blackbox

Medicine

• Any of a number of devices developed and sold by Albert Abrams, based on the pseudo-science of radionics.

• Black Box (1978 film), American film by Scott B and Beth B
• Black Box (2002 film), Argentine film (Caja Negra)
• Black Box (2013 film)
• Black Box (TV series), a 2014 ABC television series
• Black Box (The Outer Limits), an episode from the 1995 revival of that TV series
• Survival in the Sky, a TV series on the investigations of aviation accidents known as Black Box in the UK
• The Black Box (2005 film), a French mystery film
• The Black Box (serial), a 1915 film serial

• Black Box (game), board and computer game
• Blackbox (video game), an iOS puzzle game
• EA Black Box, the video game studio formerly known as Black Box Games
• The Black Box, a canceled video game; See The Orange Box

• Black Box (novel), by Israeli writer Amos Oz
• Black Box (comics) a fictional character in the Marvel Comics Marvel Universe
• Black Box (short story), a short story by Jennifer Egan
• La boîte noire ("The Black Box"), a Spirou et Fantasio comic album
• The Black Box (novel) by Michael Connelly
• Blackbox (novel) by Nick Walker