A multifaceted personality, she is not only a renowned theater artist but is also a well known name in Pollywood (Punjabi Cinema in India) and Bollywood. Her debut movie was Pal Do Pal Ka Saath (1978) with Shekhar Kapur. After that she acted in various movies Aarambh, Lava, Hawayein to her credit in Bollywood. She is a well-known face on Doordarshan and has worked in some of the most-appreciated works such as The Far Pavilions (1984), Nukkad (1986), Vikram Aur Betaal (1988), etc. Punjabi cinema, being her forte, has contributed a lot to her success with movies including Kachehri, Gabbroo Punjab Da, Dhee Rani, Suneha, Veera, Takraar, Chann Pardesi, and Khushiaan.

Rama had shot to fame in the region (Punjab) with her roles in Chann Pardesi and Kachehari, both national award winning feature films in Punjabi. However, she got national level recognition as an actress through much popular teleserial Nukkad way back in 1985. Despite her acting talent Rama could not do well in the Bollywood but still she managed to leave her mark in some well-known movies, such as Veerana, Joshiley, Prem Qaidi, Lava, and Taxi Taxie (1978).

She has worked in over 25 good teleserials including Nukkad, Intezar, Manoranjan, Himalaya darshan, Rishte, Circus and Zindagi, Misaal, Sabko khabar hai sabko pata hai , Sanjha chulha and Chunni.

Her last appearance in a Bollywood movie was in the feature film Hawayein, directed by Ammtoje Mann. Her last Punjabi movie was "Khushiaan" (2012).