At the 2012–13 Caribbean Twenty20, Ambris played two matches for the Combined Campuses, against the Leeward Islands and Jamaica. His first-class debut came during the 2013–14 Regional Four Day Competition, when he played for the Windward Islands against Guyana. In his first innings, Ambris scored 114 runs from 200 balls, eventually being named man of the match. He finished his debut season with 468 runs from six matches, making him the Windwards' leading run-scorer behind Devon Smith.

In March 2017, during the 2016–17 Regional Four Day Competition, he scored a double century for the Windward Islands against the Leeward Islands. In the 2016–17 Regional Super50, he was the top run-scorer for the Windward Islands, scoring more than double the number of runs of any of his teammates, with 423 in total.

Ambris played for the West Indies under-19s at the 2012 Under-19 World Cup in Australia. Against Papua New Guinea, he scored 91 from 43 balls, including nine fours and seven sixes.

In June 2017, he was added to the West Indies One Day International (ODI) squad, ahead of the third match against India, but he did not play. He made his ODI debut for the West Indies against England on 29 September 2017, scoring an unbeaten 38 from 27 balls.^[10]

In November 2017, he was named in the West Indies Test squad for their series against New Zealand.^[11] He made his Test debut for the West Indies against New Zealand on 1 December 2017 and became the sixth batsmen to be out hit wicket off the first ball, and the first to be dismissed in this manner on Test debut.^[12][13] In the second innings, he opened his account with a six and became only the sixth batsman in Test cricket to do so.^[14] On December 10, 2017, he got out hit wicket again in the second innings in the second Test against New Zealand^[15] and became the first player to be dismissed hit-wicket twice in consecutive Tests.^[16]In the second innings, he retired hurt (not out) after he fractured his forearm.